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What is the difference between the body of the stomach and the fundus of the stomach?

2025-11-14 02:54:25 healthy

What is the difference between the body of the stomach and the fundus of the stomach?

The stomach is one of the important organs in the human digestive system and consists of multiple parts. The gastric body and fundus are two key areas. Although they are both parts of the stomach, there are significant differences in their anatomical location, physiological functions, and possible diseases. This article will analyze the differences between the gastric body and fundus in detail to help readers better understand their structure and function.

1. Differences in anatomical locations

What is the difference between the body of the stomach and the fundus of the stomach?

partsLocation description
gastric bodyIt is located in the middle of the stomach, accounts for most of the stomach volume, and connects the fundus and antrum of the stomach.
fundus of stomachLocated in the uppermost part of the stomach, near the cardia, usually beneath the left diaphragm.

The gastric body is the main part of the stomach responsible for holding food and performing initial digestion. The fundus is located at the top of the stomach and usually stores gas after eating.

2. Differences in physiological functions

partsMain functions
gastric bodySecretes gastric acid and pepsinogen and participates in the mechanical and chemical digestion of food.
fundus of stomachMainly secretes gastrin (a hormone), which regulates gastric acid secretion and gastric motility.

The function of the gastric body focuses more on digestion, while the fundus of the stomach is more involved in hormone regulation and the balance of the gastric environment.

3. Differences in common diseases

partscommon diseases
gastric bodyGastritis, gastric ulcer, gastric cancer (diffuse type)
fundus of stomachGastric varices (commonly seen in portal hypertension), gastric gland polyps

Diseases in the body of the stomach are mostly related to digestive function, while diseases in the fundus of the stomach may be related to blood circulation or special types of polyps.

4. Differences in histological structure

partsMain cell types
gastric bodyChief cells (secret pepsinogen), parietal cells (secret gastric acid)
fundus of stomachFundic gland cells (secret mucus and gastrin)

From the perspective of cell composition, the differences between the gastric body and the fundus of the stomach are also obvious, which directly determines their functional differences.

5. Differences in imaging manifestations

partsImage features
gastric bodyIn X-ray barium meal examination, it is shown as the central part of the stomach with obvious peristalsis.
fundus of stomachGas accumulation is often seen under X-ray, forming gastric bubbles

In imaging examinations, the performance of the body of the stomach and the fundus of the stomach are also significantly different, which helps doctors make an accurate diagnosis.

Summary

Although the gastric body and fundus are anatomically adjacent, they have significant differences in location, function, disease type, tissue structure, and imaging manifestations. Understanding these differences not only helps us better understand the human digestive system, but also has important significance for the diagnosis and treatment of related diseases. The body of the stomach is mainly responsible for the digestion of food, while the fundus of the stomach is more involved in endocrine regulation. In clinical practice, doctors will accurately determine the location of the disease based on symptoms and examination results, so as to formulate more targeted treatment plans.

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